How to prevent steroid induced osteoporosis.
نویسنده
چکیده
The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.
منابع مشابه
[Current indications for prevention and therapy of steroid-induced osteoporosis in men and women].
Steroid-induced osteoporosis is a textbook example of the secondary type of this medical condition. Glucocorticosteroids suppress bone formation by their direct and indirect effect on osteoblasts, osteoclasts and osteocytes, increasing their resorption and, eventually, leading to negative bone balance. A clinical problem arises regarding the fact that approximately 50% of patients on chronic st...
متن کاملOsteoporosis prophylaxis during corticosteroid treatment: failure to prescribe.
AIMS To investigate prescribing patterns to prevent steroid induced osteoporosis. To compare prophylactic prescribing with National Osteoporosis Society (NOS) guidelines. METHOD All patients (n=92) taking oral corticosteroids admitted to general medical wards at a district general hospital were prospectively investigated over a nine month period. RESULTS Variations from recommended manageme...
متن کاملPossible prevention and treatment of steroid-induced osteoporosis.
Patients with steroid-induced, juvenile and senile osteoporosis were studied using balance techniques. The changes in calciun and phosphorus balance associated with glucocorticoid therapy were corrected with vitamin D and bendrofluazide given in combination. No hypercalcaemia occurred in osteoporotic patients who continued to receive glucocorticoids. Calcium and phosphorus balance was also impr...
متن کاملPrevalence of long term steroid treatment and the frequency of decision making to prevent steroid induced osteoporosis in daily clinical practice.
BACKGROUND The use of oral corticosteroids (CS) is one of the most common causes of iatrogenic osteoporosis. Recently, therapeutic guidelines dealing with the skeletal complication of CS have been published. OBJECTIVE To evaluate how CS are used in the community and the frequency of active intervention against corticosteroid induced osteoporosis in daily clinical practice. MATERIAL AND METH...
متن کاملSymptomatic refractures after vertebroplasty in patients with steroid-induced osteoporosis.
BACKGROUND AND PURPOSE Refracture after percutaneous vertebroplasty in patients receiving oral glucocorticoid therapy has caused some patients and referring physicians to have negative perceptions concerning the efficacy of the initial vertebroplasty treatment. The purpose of this study was to analyze symptomatic refractures after vertebroplasty in patients on oral steroid therapy. We hypothesi...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 64 2 شماره
صفحات -
تاریخ انتشار 2005